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Patient 13 is the final boss on the map Terminus in Black Ops 6, appearing as a giant mutated kraken like creature who was another experiment of Dr. Modi known as Owen Guthrie.
Patient 13 is a dynamic boss fight, changing elemental weaknesses depending on which phase of the boss fight you are on, as each of his weak points has a different elemental weakness.
During the first phase, the Red Cysts on his shoulders are weak to 
Napalm Burst, during the second phase, the glowing parts on his tentacles are
weak to 
Dead Wire and 
Light Mend, while his mouth when glowing, is weak to 
Cryo Freeze.
During his final phase, his glowing blue eyes on his head are weak to 
Shadow Rift and 
Brain Rot
meaning you can't go wrong with any ammo mod you decide to bring into the boss fight. For more information on how to complete the main quest, prepare for the boss fight,
and defeat the boss, you can read our detailed guide for the Terminus main quest, No Mo' Modi.
Nathan Aguinaldo is a mini-boss originating on the map Terminus in Black Ops 6, serving as Maya's younger brother who was experimented on by Dr. Modi for Project Janus.
Doppelghasts are violent and display erratic and unsettling movement, as if each head is independently fighting for control of its body. Originating from the map Citadelle Des Morts in Black Ops 6.